Yes, you can deduct both if you itemize your deductions.
To deduct your registration fee, it must be based on the value of your vehicle.
See Is Your Car Registration Deductible
https://turbotax.intuit.com/tax-tips/tax-deductions-and-credits/is-your-car-registration-deductible/...
To enter car registration fees:
· Type in car registration fees in the search box, top right of
your screen, hit
the Enter key
· Click jump to car registration fees in the search results
· Follow the
prompts and online instructions
To enter sales taxes paid, type in those exact words and follow the above instructions
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