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It depends.
The IRS gives many definitions of what is and is not a medical expense. I think clothing items that were required due to the mastectomy (mastectomy bras, etc) would fall into the category below:
Items that were not medically necessary would most likely not be deductible.
The IRS allows you to deduct qualified medical expenses that exceed 7.5% of your adjusted gross income for 2017 and 2018. You can add medical expenses under "deductions and credit."
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