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It depends. According to the IRS:
A permanent disability is a physical or mental condition that prevents you from engaging in substantial gainful activity and that a physician determines has lasted or can be expected to continuously last for at least a year or can lead to death.
To claim the credit, you must have a statement from your physician certifying that you are permanently and totally disabled.
Here is a TurboTax article with more information on disability tax credits and the definition of permanently disabled.
income bar is very low even if you qaulify
There is an extra amount added to your standard deduction if you are legally blind. Your federal return does not provide any other credits or deductions for saying you are disabled, with one possible exception.
There is a credit for the Elderly and Disabled which is so small that very few people benefit from it—-it has not been updated/increased by Congress for decades.
ELDERLY OR DISABLED CREDIT https://www.irs.gov/help/ita/do-i-qualify-for-the-credit-for-the-elderly-or-disabled
There are some states that provide various credits to elderly/disabled folks, so watch for that when you prepare your state return. The states that I know of that have anything for elderly/disabled are AZ, CT, DE, IA, MO, ND, NJ, NY, VE. There may be others.
You do not mention why you are asking about Alzheimers. Do you have a spouse or dependent who is being entered on your tax return who has Alzheimer's?
An additional comment---if you are claiming someone as a dependent -- or filing a joint return with-- who has a disability that is such that you must pay someone to take care of them while you work, you may be able to enter the child and dependent care credit for them.
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