The one-time exemption has not been the law for a long time. That provision has been replaced with a more complicated exclusion of up to $250,000 gain (not sale price) exclusion if you qualify. (usually $500,000 if you are married.)
Details are here:
http://www.nolo.com/legal-encyclopedia/the-250000500000-home-sale-tax-exclusion.html
For how to enter in TT, see this:
https://ttlc.intuit.com/questions/2744791-where-do-i-report-sale-of-primary-home
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