Yes, if your instructions say you need to mail the form to the IRS, then you should do so.
This would happen if you entered sales section totals in the Schedule D area of your return and one of the categories was something other than category A (short-term covered) or D (long-term covered) or if there were adjustments included in boxes 1f or 1g on your broker statement.
See the following TurboTax help article for more information:
Do I need to fill out or mail in Form 8949?
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