You don't say what kind of business the home office's relate to. Out of pocket expenses for a W-2 job are no longer deductible. That includes a home office.
If you each have your own separate SCH C business, then the home office for each business is dealt with separately for each business. So when entering the SCH C for your business you'll deal with your home office there. Then when entering the SCH C for the wife's business you'll deal with her home office there.