Can I deduct expenses for a conference necessary to my work? Includes unreimbursed portion of conference fees, supplied meals, and hotel.

[Opus 17]

Unreimbursed business expenses are deductible as itemized miscellaneous deductions subject to the 2% rule, so your actual benefit will be reduced and subject to your other tax situations.

You can deduct expenses that are ordinary and reasonable in your line of work.

For travel away from home, you can deduct actual travel expenses, actual lodging expenses, and either 50% of your actual food cost, or 50% of the federal per diem meal rate for the location you traveled to.  I believe that if you list all your meal expenses, turbotax will perform the 50% adjustment.  You can also deduct conference registration.

[JoshuaT]

This link will provide you the guide lines provided by the IRS regarding business expenses.
https://www.irs.gov/businesses/small-businesses-self-employed/deducting-business-expenses#what