Yes, you would be able to deduct Weathertech Mats, as this could easily be considered an ordinary and necessary expense for your business. However, this would also be part of the maintenance of a vehicle so you would not be able to deduct it on top of the Standard Mileage Deduction. You would need to enter actual expenses to deduct the Mats.
https://turbotax.intuit.com/tax-tips/self-employment-taxes/standard-mileage-vs-actual-expenses-getti...
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