No, you should wait until your return has been fully processed. Once the IRS has accepted and processed the return, you should amend your return with the changes and send payment for the amount that will be owed. If the IRS does sends you the original refund, you can hold on to the refund until after you complete your amended return, and send the amount that was overpaid in error back with the amended return (in the check, money order or credit card payment you use).
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