Previously purchased ISO options to zero - loss?

[sharvs]

Hi,

Quick question on if I am able to somehow report this is a loss and deduct it from my taxable income?

Over the past several years, I have exercised many ISO stock options for my startup company. The company was acquired, but not for enough $$, so the value of my shares went to zero.

Is there any way to report the $$ spent on the options as a loss?