Hi Patrick, based on those numbers, it appears that the taxable gain on the sale of your home will be about $28k. The good news about that is that it's a Long-Term Capital Gain and for a Single person with Taxable Income under $41,675, the tax rate is 0% (Zero). That Taxable Income amount is generally your income minus deductions (that's at least $12,950 or 14,350 if 65+ years old). Based on what you wrote abut question #2, it seems you're likely to have Taxable Income below that $41,675 amount. If not, the excess will be taxed at 15%.
As for Question #2, the answer depends on the source of the disability income you're receiving. Here's a good article that explains: Is disability income taxable?
For Question #3, no the capital gain from the sale of your home can't be reduced because of your purchase of the RV. There are no tax benefits of it now being your primary home although the sales tax you paid is a potential itemized deduction (although choosing the Standard Deduction may still be more beneficial).
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