Since your son is under 23 and a full-time student, he has to indicate that he can be claimed as a dependent even if he isn't.
Gambling winnings are considered unearned and subject to "kiddie tax", which means the tax rate is determined by the tax rate of the parents. However, this shouldn't cause the federal tax due to be more than double the winnings if the W-2G is the only income that your son received.
If there are other items of income combined with this, you could see a pretty big jump in tax when this item is entered.
If it's the only item of income I would clear the return and start over, after taking a moment to file an extension to get a little extra time to avoid "failure-to-file" penalties.
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