It depends. If your home qualifies as your principal place of business, then the mileage from home to the self-employed work locations and back is deductible on Schedule C. Otherwise, it is considered to be commuting miles and is not deductible.
If you traveled between locations for the self-employed work, then those miles would be deductible on your Schedule C.
To learn more about what it means to have your home qualify as your principal place of business, see the following TurboTax help article:
What qualifies as "Principal Place of Business" for the home office deduction?
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