Yes, If the 1099-S was for the sale of your main home, it’s reported under Less Common Income in the Wages & Income section. Here's how to enter the form:

Open or continue your return
Type sale of a home in the Search box
Select the Jump to link in the search results
Follow the interview to enter the info from your 1099-S

Profits of up to $250,000 ($500,000 on a joint return) on the sale of your home may not be taxable if it was your primary residence for two of the last five years. We’ll ask you some questions about the sale of your home to see if you qualify.

IRS Instructions for Form 1099-S

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AndreaC1

Level 11

Okay, see my response below.

AndreaC1

Level 11

You may get a 1099-S if you sold timber, real estate (including land), permanent structures, or stock in a co-op.

You can follow the steps here below to help you enter that 1099-S for sale of land. It will have you search for sold second home but you will see the option to choose land on the 3rd page. Just follow each step exactly.

NOTE: See screenshots below for help navigating.

https://ttlc.intuit.com/replies/4241480