No. Home improvements to your own home are not deductible; money you took from your retirement account is taxable. If you took money out of the 401k in 2020 you will soon receive a 1099R that must be entered on your tax return.
To enter your retirement income, Go to Federal> Wages and Income>Retirement Plans and Social Security>IRA 401 k) Pension Plan Withdrawals to enter your 1099R.
**Disclaimer: Every effort has been made to offer the most correct information possible. The poster disclaims any legal responsibility for the accuracy of the information that is contained in this post.**