Can i deduct school expenses like software for classes even if I use the standard deduction?

[Hal_Al]

There is no deduction for school expenses, either itemized or other, on the federal return.  Some states have a deduction, if that's what you're asking about, you need to identify the state. 

There are a couple of federal educational credits available.  Tuition, fees, books and "other required course materials" are qualified expenses.  A computer is usually allowed. Whether the cost of software is allowed would depend on meeting the "required by the school" rule.