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Itemizing and capital gains are separate issues so one doesn’t affect the other. If you are expecting significant gains be sure that you have paid enough estimated or withholding tax to cover the gains for federal and, if applicable, state income tax.
I don't know what you mean by a "Tax Loss Harvesting Deduction." There is no such deduction. Tax loss harvesting simply means selling stocks that have declined in value to offset the gain from selling other stocks that have increased in value. The capital losses offset the capital gains when calculating your income. This has nothing to do with using the standard deduction or itemized deductions.
@afsteven0513 simply, your capital losses are netted against your capital gains. If there are more losses than gains, up to $3000 can be used to reduce your ordinary income. if there are still dollars remaining, that is a tax loss carry forward and you can use that remaining loss against future gains and up to $3000 against ordinary income.
as others have stated the losses have nothing to do with itemizing./
Itemizing is Schedule A and Capital Losses are Schedule D
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