Can I deduct mortgage interest used to payoff an existing mortgage...

[willmpdx]

I had a loan on my home for $150,000 - I'll call it Property A. In 2020 inherited another property that had no debit - I'll call it Property B.

In 2020 I moved into Property B and made it my primary residence. In 2021 took a loan on Property B for $200,000 to pay off Property A and make improvements to Property B. The new lender issued a check to the other lender to close the loan on Property A and issued me a check for the remainder. 

Since $150,000 of the new loan was used to pay off another debit (Property A), do I lose the mortgage interest deduction on that loan?       

[RobertB4444]

Nope, you're all good.

The IRS allows a qualifying mortgage interest deduction on loans secured by the property of a first or second home up to $700,000.  Nothing in your question would seem to disqualify you.

The deduction can get super complicated so if you have a bunch of other factors that aren't in your question be sure to check the IRS out here.