Yes you can. But it's not what you may think. You don't "integrate" anything. To file your Canadian tax return, you have to use the Canadian version of TurboTax. To file your U.S. tax return, you use the U.S. version of TurboTax. Neither program integrates in any way, form or fashion with the other. However, while I know nothing about TTX Canada, I do know that with the U.S. version it does allow for and take into consideration any foreign taxes you pay have paid to other countries, including Canada.