go back and re-check box 2 for Federal (On the actual software form). A decimal point for cents 81.23 entered as 81comma23 will turn into $8123.00.
Watch those keyboard entries. Take a double-look on every box in that software form again too.....there could be others, for which you also hit the comma .
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Still wrong? Delete the entire W-2, and then re-enter again from scratch (