If you owned stock in a company that went bankrupt and the stock became worthless, enter it as a sale of stock in the Stock, Mutual Funds, Bonds & Other interview of Federal Taxes > Wages & Income > Investment Income.
Don't own stock, it was a start up company.
Enter it in the investment sales (disposition) section of TurboTax.
When you sell stocks, bonds, mutual funds, or other securities, you should get Form 1099-B.
But what about non-security investment sales like coins, collectibles, timber, land, or a second home? Here's how you enter those:
Source: TurboTax FAQ