Additional taxable withdrawals from an IRA will be added to your income. Your IRA custodian will probably withhold more tax as well.
To get in touch with a Tax Expert, click on What is the TurboTax phone number?
You can also use TurboTax's free Taxcaster to estimate your 2022 taxes. It's programmed for 2021 but at this time, but it can give you a good estimate.
There is also a place within TurboTax to perform estimates. For help, click on Can TurboTax calculate next year's federal estimated taxes?