Are you Efiling your Federal and State returns separately? If so, here's more info on Filing Federal and State Returns Separately.
Make sure you have disabled all anti-virus software (including modem), are using TurboTax on your C drive (including saved files), and are running as Administrator.
Here's more info on Troubleshooting TurboTax Desktop Issues.
If you're using TurboTax Online, try closing the program, clearing your Cache and Cookies and retry. This usually resolves Efile errors.
If you're having the issue Efiling state, try deleting your state, redownload, and step through the state interview to repopulate it. Here's How to Delete a State in TurboTax Online and How to Delete a State in TurboTax Desktop.
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