If your spouse is a nonresident alien, you have two options:
- either treat your nonresident spouse as a U.S. resident for tax purposes.
- or file as Head of household if you pay more than half the cost of maintaining a household for certain dependents or relatives other than your nonresident spouse.
Please read this IRS document for more information.
As your spouse has no ITIN, you have to apply for an ITIN for your spouse if you wish to treat her a resident alien for tax purposes..
Please read this TurboTax Help topic on How to file your tax return with a W-7.
You cannot e-file. You have to file by mail or in person.