On my federal withholding, I am claiming 6 dependents...my wife, who does not work, and my 5 kids. Will I lose out on all of those exemptions under the new tax law?

All Personal Exemptions go away effective with the 2018 tax year (returns filed in early 2019). But you get a larger Standard Deduction and larger Child Tax Credits.

https://www.irs.gov/newsroom/updated-2018-withholding-tables-now-available-taxpayers-could-see-paych...

Thank you.  So does that mean I should go into my federal withholding information at work and change it to show no exemptions? I don't want to get to January 2019 and have a refund that is a lot less than what I'd normally get.  Sorry...just a bit worried.  I'm the only person in the house who has an income.