No W2 Income for Next Year - How Do You Adjust The 1040-ES Payment Voucher Calculation?

Turbo calculates four(4) 1040-ES payments with 'vouchers'. This is a calculation based on current (last years) W2 withholdings to get a user within 100% of last years total taxes to be within safe harbor from penalties.

But what if you retire or plan to retire? Your W2 withholdings may be dramatically reduced from what was used in calculating the estimated payment vouchers. To be in safe harbor do you need to re-calculate the estimated payments to be equal with what your W2 withholdings would have been?

E.g. if based on last years return, Turbo estimates you need to pay $18,000 in total taxes to be in safe harbor. It expects say $10,000 in W2 withholdings. You  will need $8,000 in est payments (4 payments @ $2k/ea) and prints out 4 vouchers at $2k. ea. But you retire on Jan 1. No W2 income or withholdings. You plan to make up for that lost income with say investment or rental income or social security or something. To be in safe harbor do you now have to make 4 estimated payments of $4,500 each for a total of $18,000?

Thanks