For married filing separately, You and your spouse must both file the same way. If one itemizes, the other must itemize. Same for standard deduction.
You and your spouse may be able to save money by filing jointly, if that is feasible.
The determining factor is itemization, If either one of you itemizes your deductions the other person must also itemize.
This TurboTax link https://How can we compare married filing jointly with married filing separately? will allow you to see which filing will provide you with the least overall tax liability.
This issue may not be resolved in time for you to file your taxes by the April 18, 2022 deadline. You may want to consider filing an extension to file you’re your tax return. This TurboTax link How do I file an IRS extension (Form 4868) in TurboTax Online? will assist you in filing an extension.
IRS extensions for tax year 2021 must be filed on or before April 18, 2022 for domestic taxpayers.
Keep in mind: An extension doesn't give you extra time to pay your taxes — but it will keep you from getting a late filing penalty.
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