is there an advantage to use 1040 SR if over 65 years old? if there is an advantage, does turbotax siftware use that when filing the federal return?

No, there is no advantage and no real difference.   The only difference is the size of the font.  The print is larger which makes the standard deduction table easier to read.  And yes, TurboTax will use 1040-SR if you are over 65.