This is a known problem. See this TurboTax support FAQ - https://ttlc.intuit.com/questions/4205245-getting-rejection-code-f1040-021-01-for-negative-amount-fo...
Why was it rejected, what is the rejection code?
This is what it says:What happenedF1040-021-01 - If Schedule A is present in the return, then Form 1040, Line 40 Itemized Deductions Or Standard Deduction must be equal to Schedule A, Line 29 Total Itemized Deductions.