I have an estimated tax penalty (1040 line item 38) even though I withheld and prepaid estimated taxes totaling to 92% of my 2022 tax and 110% of my 2021 tax. Any ideas?

Go through the Underpayment tax penalty section of the program to see if spreading the payments out throughout the tax year will reduce or eliminate the penalty using Form 2210.

Click on Federal on the left side of the online program screen.

Click on Other Tax Situations

Under Additional Tax Payments

On Underpayment Penalties, click on the start button

did you make even estimated tax payments each quarter and were they timely? withholding, if any, is deemed that 25% is paid each quarter but you can use actual withholding for each period

estimates are due 4/15, 6/15, 9/15 and1/15 of following year

if uneven you can try to use the annualized installment method to see if that lowers the penalty