How do I send quarterly estimated tax payments to the IRS during this year 2021 for when the taxes are due in April 2022? How does one know how much to send each quarter?

TurboTax can calculate your 2021 estimated taxes and allows you estimate your 2021 income and deductions in order to calculate and create estimated tax payments.

Please follow these steps to calculate and generate 1040-ES vouchers: 

1. With your tax return open, search for 1040-es (be sure to include the dash) and select the Jump to link.
2. Answer No to the question Do you want to change your W-4 withholdings for 2021?
3. Answer the questions about things like your 2021 filing status, income, and deductions.
4. Eventually, you'll come to the Print Vouchers? screen. Answer Yes and we'll include your 2021 1040-ES payment vouchers when you print a copy of your return later.