Subleasing income is rental income and is reported on Schedule E. It is not subject to self-employment tax.
Business income is reported on Schedule C and is subject to self-employment tax.
So if you report the rental income on Schedule E you will need to allocate your office rent between the Schedule E activity and the Schedule C activity.
As an example, your monthly office rent is $5,000 and you are subleasing 20% of your office space. You should allocate 20% of your monthly office rent or $1,000 to the Schedule E and 80% of your monthly office rent or $4,000 to Schedule C.