Yes, you can deduct the wages paid to a casual laborer who earned less than $600 for the entire year without having to file a Form 1099-MISC. If possible you should maintain for your records the name, address and SSN for these workers.
If you are referring to paying someone as a personal expense, such as paying a handyman for completing a project on your home, than no deduction is available.
If you are the owner of a small business and report business income and expenses, then contract labor is a deductible business expense. To enter the labor as a business expense:
Contract labor paid $600 or more requires the issuance of a 1099-NEC.