When entering expenses for 1099 Do I use monthly amounts or yearly amounts for expenses for entire home?

Enter the yearly expenses.

If you are referring to self-employment expenses, follow the instructions in the TurboTax help article Where do I enter my self-employment business expenses, like home office, vehicle mileage, and supplies?

Refer to the TurboTax articles The Home Office Deduction and Where do I enter the home office deduction for my business?  for specific  information regarding the amounts to enter for your home office.