I worked 2 full time, 100% remote jobs in 2022. Can I take any deductions for both jobs? For instance home office credit or credit for any expenses for each?

It depends if you are paid as a W2 employee or as an independent contractor and received a 1099-NEC.  If you received a W2 to report your pay, you cannot deduct any unreimbursed business expenses or home office expenses.  If you received a 1099-NEC to report your pay the IRS considers you self-employed and you need to report your income on Schedule C, where you can also deduct business expenses and the home office deduction.

See Am I considered self-employed? and What self-employed expenses can I deduct? if you are indeed self-employed.

You can’t deduct the full amount twice.  For a common expense like home office split the total cost as a percentage attributed to each business.