I can seet Self Employment Income is positive on the Wages & Income Summary page. Not sure where the Net Profit is being pulled from, maybe that's the problem.
The Home Office deduction can't increase your loss, so you can't take it if your business' net income is negative. The amount that shows on the Wages & Income is the gross income, not the net income. The net income is your income after your business expenses. You should review your 1040 and review your Schedule C which is the form where your self-employment is reported and see what your net income is.
The amount that will need to be positive for you to take Home Office deduction will be on line 29 on Schedule C. To review your return: