If your state allows, then yes.
States where you claim personal property tax in lieu of vehicle registration fees
Although auto registration fees aren’t deductible in the following states, you're allowed to claim the personal property tax you paid annually based on the value of your car.
Follow this link to learn more about the Personal Property Tax Deduction.
Arkansas The Ad Valorem Tax paid to your county based on your vehicle’s value
Connecticut The Property Tax you paid to your city or county based on your vehicle's value
Kansas The Personal Property Tax you paid to your county based on your vehicle's value
Maine The Excise Taxes you paid to your city or county based on your vehicle's value
Rhode Island The Excise Tax paid to your city or town based on your vehicle’s value
Virginia The Personal Property Tax paid to your city or town based on your vehicle’s value
West Virginia The Personal Property Tax paid to your county based on your vehicle’s value
For Registration:
You can deduct it if it’s a yearly fee based on the value of your vehicle and you itemize your deductions.
You can’t deduct the total amount you paid, only the portion of the fee that’s based on your vehicle’s value.
And, not all states have value-based registration fees. The states that do are listed below along with the deductible portion of your registration fee.