Usually a 401K is fully taxable and a 10% Early Withdrawal Penalty for distributions. There is no exception for buying a home. That's only for IRA withdrawals.
You will get a 1099R for it.
The easiest way to get to the 1099-R entry screen is to simply search for 1099-R (upper- or lower-case, with or without the dash) in your TurboTax program and then click the "Jump to" link in the search results.
Enter a 1099R under
Federal Taxes Tab or Personal (Home & Business)
Wages & Income at the top
Then scroll way down to Retirement Plans and Social Security,
Then IRA, 401(k), Pension Plans (1099R) - click Start or Revisit
If you are filing a Joint return be sure to pick which person it is for.
Don't enter the bank or broker name and don't try to import it. It is just as fast and easy to manually enter it. At the bottom pick - Change How I enter my Form
Then on the next screen pick I'll Type it in Myself
There is not an exception to the early withdrawal penalty when the withdrawal is from a 401(k) account for a first time home purchase. The exception is only if the withdrawal was from an IRA and then only the first $10,000 can be excluded from the penalty.
To enter, edit or delete a form 1099-R -
Or enter 1099-r in the Search box located in the upper right of the program screen. Click on Jump to 1099-R