Whata fom does Turbo tax use to calculate capital gains from sale of residence?

the sale info flows to form 8949 where any home sale exclusion is reflected then that flows to scheduled D 

The interview in TurboTax Premier will guide you through calculating the gain on the sale of your home. It includes an EasyGuide to help you calculate your cost basis. The interview and EasyGuide will suggest all the costs that you should enter.

In the Search box type "sale of home" (without the quotes), then click the link that says "Jump to sale of home."

If the 1099-S was for the sale of your main home, it’s reported under Less Common Income in the Wages & Income section. Here's how to enter the form:

• Open your return.
  (To do this, sign in to TurboTax and select the blue Take me to my return button.)
• Type “sale of home” in the Search box.
• Select the “Jump to” link in the search results.
• Follow the screens to enter the info from your 1099-S.

Profits of up to $250,000 ($500,000 on a joint return) on the sale of your home may not be taxable if it was your primary residence for two of the last five years. We’ll ask you some questions about the sale of your home to see if you qualify.

You should have a copy of the purchase HUD statement, the sales HUD statement, a total of any improvements you made  in hand for reference ... just follow the interview screens.