In the Windows Desktop Home & Business program you can prepare them 2 ways, using Quick Employer Forms or doing them on your desktop.
If you use the built in W2/1099 reporter inside the Desktop Home & Business program you can only print and mail them. If you don't have many, you can renter it again into Quick Employer Forms so you can efile the forms to the IRS.
How to create W2s and 1099
https://ttlc.intuit.com/community/forms/help/how-do-i-create-w-2-and-1099-forms-in-turbotax/00/25869
