On 1040 Schedule D, the very first Yes/No question is not answered (neither "yes" or "no" is marked). The answer is "no". Does it need to be marked?

Yes, you do need to answer the question on Schedule D. 

• Did you dispose of any investment(s) in a qualified opportunity fund during the tax year? Yes or  No If “Yes,” attach Form 8949 and see its instructions for additional requirements for reporting your gain or loss.

Definition:

A Qualified Opportunity Fund is an investment vehicle that is organized as a corporation or partnership for the purpose of investing in Qualified Opportunity Zone property (other than another Qualified Opportunity Fund).

Thank you DianeW777, but my question was misunderstood (given the limited characters to ask). I ended up calling tech support as I believe it is a software "bug". The fact is a I could NOT answer the question, no opportunity given. Fortunately my answer to the question is "no", so given that the software will not mark either answer, a non-answer is considered a "no" to the IRS. So I will be submitting my 1040 with neither "yes" or "no" marked.