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The IRS doesn't want you to amend until you've already gotten your tax refund or your payment has been processed. If you will owe money after amending, include payment with your e-filed or mailed amendment form.
There are times when you should amend your return and times when you shouldn't. Here are some common situations that call for an amendment:
See this article and this one for more information on filing an amended return with TurboTax.