I filed my return electronically 6 weeks ago and am still waiting on my refund. However, when I went back into turbo tax my refund amount has changed. Do I need to file an amended return?

You are asking from TT Business; which is used for S Corp, C Corp, Partnership and Estate/Trust returns.

But if you are really asking about your personal tax return, did you report a 1099-G for unemployment comp?    You do not need to amend for Federal.

IRS chief: Unemployment recipients shouldn't file amended tax returns - News Break

But see these re State:

How is my state taxing unemployment income? (intuit.com)

Do I need to amend my state return to update my un... (intuit.com)