Hello, @I2giveupsurrender , great question!
Usually, it is advisable to withhold taxes from your unemployment benefits so that you don't end up owing taxes at the end of the year. The good news is, if the withholding is more than what you end up owing for the year, you will receive a refund of the difference!
Unless you are sure that you will not owe a tax balance next year (you can estimate here), I would suggest opting in to tax withholding.