The only change for 2022 is that the life-expectancy tables have been updated for 2022 and beyond, so make sure that you are using the updated life-expectancy table when calculation the amount of your RMD. Market performance during 2022 has no effect on the calculation of your RMD for 2022 but having a lower 2022 year-end balance will reduce the amount of the RMD that you would otherwise have for 2023. It's not a bad idea to have some amount of your retirement income invested in relatively stable funds from which you can take the RMD without worrying about taking the RMD during a down market.