You can e-file after entering the 1099-R on your tax return.
The taxable amount shown in box 2a of the 1099-R is entered on your tax return as taxable income and taxed at your current tax rate. The federal income taxes paid shown in box 4 are entered on your tax return as a tax payment (just like withholding from a W-2). The taxes withheld are estimates of the taxes owed. When the taxable income from the 1099-R is added to your other income you may receive a tax refund or you may have taxes owed.
