Yes you should send in an estimated payment so you don't owe too much on your tax return or get hit with a penalty.
Here are the 1040ES instructions and blank forms (where to mail is on page 4)
https://www.irs.gov/pub/irs-pdf/f1040es.pdf
Or you can pay on the IRS website. Be sure to pick 2021 1040ES payment
https://www.irs.gov/payments
