Depends. If you need to file a 1120 or 1065 return you file it separately. If you have self employment income or a Single Member LLC (that is not a S corp) it is a disregarded entity and you file it on Schedule C in your personal 1040 return. You can't file it by itself.
You can enter Self Employment Income into Online Deluxe or Premier but if you have any expenses you will have to upgrade to the Self Employed version.
How to enter income from Self Employment
https://ttlc.intuit.com/community/self-employed/help/how-do-i-report-income-from-self-employment/00/...
