Well all your deductions like Mortgage Interest, property tax, Medical, Charity etc. have to be more than the Standard Deduction to give you any benefit. The first year you buy a house you might not have enough interest to itemize. You might have enough the second full year.
For 2023 the standard deduction amounts are:
Single 13,850 + 1,850 for 65 and over or blind (15,700)
HOH 20,800 + 1,850 for 65 and over or blind (22,650)
Joint 27,700 + 1,500 for each 65 and over or blind (29,200/30,700)
Married filing Separate 13,850 + 1,500 for 65 and over or blind (15,350)
