The 1099-S is for the sale of ANY real property and you will NOT enter the form in the program but you will use the information on the closing statement in the asset section of the Sch E area of the interview ... you will indicate it was sold and in the asset section you will "sell" off all the assets ... if you have NOT been claiming depreciation on the assets in the past then RUN to a local tax pro to get this issue corrected properly ... the form 3115 is NOT a DIY project.
See this TurboTax support FAQ for the sale of a rental property - https://ttlc.intuit.com/turbotax-support/en-us/help-article/real-property/sold-rental-property-repor...
